FORMULATION OF GARGLE FROM TRIGONA SP. PROPOLIS EXTRACT AND ITS ACTIVITY AGAINST STREPTOCOCCUS MUTANS

Objective: In this research, the formulations of a gargle with Trigona sp. propolis extracts as an alternative dental caries therapy and test its activity against Streptococcus mutans was carried out.
 Methods: The experimental laboratory have been out following stages work, material collection processing, extraction by maceration 95% ethanol, phytochemical screening, determination minimum inhibitory concentration, formulation gargle, activity, contact time stability formulas.
 Results: Phytochemical screening showed that containing flavonoids, polyphenols, quinones, monoterpenoids sesquiterpenoids. Minimum concentration 0.25% w/v. from extract were yellow solution mint odor taste sweet. antibacterial preparation formulas market comparison, formula 1% w/v gave significant difference to preparation. has good inhibition bacteria S. 60 seconds is physically stable during 35 d storage time.
 Conclusion: excellent be developed in future treatment caries.